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M94A2356.TXT
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1994-10-25
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Document 2356
DOCN M94A2356
TI Socioeconomic characteristics are associated with rate of weight loss in
homosexual men. Vancouver Lymphadenopathy-AIDS Study.
DT 9412
AU Voigt R; Hogg RS; Craib KJ; Strathdee SA; Zadra J; Montaner JS;
Schechter MT; UBC & BC Centre for Excellence in HIV/AIDS, Vancouver,
Canada.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):322 (abstract no. PC0220). Unique
Identifier : AIDSLINE ICA10/94370219
AB OBJECTIVE: To characterize socioeconomic determinants of 5% weight loss
as an event prior to AIDS among HIV-infected homosexual men in the
Vancouver Lymphadenopathy AIDS Study (VLAS). METHODS: 650 gay men from
the VLAS with available baseline weights (217 seroprevalent-SP, 116
seroincident-SI, 317 seronegative-SN) were studied. Baseline weights
were determined from enrollment for SP and SN men, or the last visit
prior to seroconversion for SI men. 5% weight loss was treated as an
event prior to an AIDS diagnosis. Kaplan-Meier (K-M) curves were
generated stratified by serostatus. K-M curves were also plotted
stratified by baseline measures of annual income (< $10,000 or > or =
$10,000) or education (high school graduates vs. non-graduates).
Subjects were right-censored if AIDS was diagnosed, otherwise at the
data of a last recorded weight. Statistical significance was determined
by the logrank test or Wilcoxon test. RESULTS: Age, height and weight of
SN, SI and SP subjects were nearly identical at baseline (all p > 0.1).
K-M curves for SN, SI and SP men were significantly different from one
another (P < 0.0001). Among HIV+ men (SI + SP combined), subjects
reporting annual incomes < $10,000 at enrollment experienced 5% weight
loss more quickly (26/77) than men reporting higher incomes (57/252) (p
= 0.03) (see figure). There was no difference in progression to weight
loss for high school graduates vs. non-graduates (p = 0.28).
CONCLUSIONS: Our data demonstrate that low annual income was associated
with a more rapid weight loss among HIV-infected AIDS-free homosexual
men. Socioeconomic variables appear to play a significant role in
determining the likelihood of pre-AIDS clinical events. TABULAR DATA,
SEE ABSTRACT VOLUME.
DE Acquired Immunodeficiency Syndrome/DIAGNOSIS/*PATHOLOGY Educational
Status *Homosexuality Human HIV Seropositivity *Income Male
*Weight Loss MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).